Model-based Fermentation Control

Partner: Department of Biotechnology, BOKU Vienna Plant location: Vienna / AUSTRIA

Universität für Bodenkultur Wien, Österreich


  • Seamless integration into process control environment
  • Process monitoring based on neural network models
  • Integrated Database for data recording
  • Save access also from office networks
  • Data export from all clients also within office network
  • OPC interface with process control system
  • Interface to in-line analyzers

Within the yarity of production in the pharmaceutical industry fermentation – the controlled cultivation of microorganism - is one of the most complex processes.

The University of Natural Resources and Life Science, Vienna, has a long tradition in the field of biotechnology and is one of the leading universities in the field of process research and development.

Several projects focused on the development of mathematical models for the online prediction of process parameters, which can generally be obtained only through offline - lab analyses.
These so called Soft Sensors are based on c omplex mathematics, which makes the implementation using classical control systems practically impossible.

The PATControl software platform from evon combines all functionalities of typical control systems with the possibilities of complex mathematics and optimization algorithms.

The installation and start up of PATControl at the department of biotechnology was realized within some weeks. As a result the Soft Sensors deliver online measures for the research team as well and provide new possibilities for improved control loops.
The integrated database offers a easy access to all measurement results and a comfortable export for further data processing or statistical modelling is available. The user management as well as the journal leads to absolute transparency regarding what was done, who did it and at what time.


  • Rene Hirschmugl
    Area Director - Process Control Engineering
  • 0043 3178 21800-146

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